SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc33f4cf9e3ebbec6c5053e3f6b2d89972186378409c18d239a1404709cc2c4e' 
  AND token = 'MTQoAwQ6NkVNxS9RB7a/84SmKI+GL8iRpehUz9KqRGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}