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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8357c10ab2b7c1be45837ff88b03f52c4780053463e17403c06df831744084d3' 
  AND token = 'rBEk0Or/xHGN2Hw9iZlGbebl//PK/eYM4E7C+s+Ic3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}