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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1d9b640ae67d60b42c2fc3cc1d81b1b3b4e8bfdda3d48e06f5b60b26d8e9157' 
  AND token = 'ns2PSTOJVsxWm4iX5Lh+pgw0ext0lddU2I8fx1bjw/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}