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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd325b53385eac3be48d655f07914eff017f070d425d422baea5c64e31b8507b8' 
  AND token = 'di1dwuqLXY+Vmh2J4qYkXxiSbsi09DCIIFGY0iC3zNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}