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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '668f9875a2b70da752f5130470ec008c7c3fb75a2e635c6301308d52d6516d4d' 
  AND token = 'PFFPxYVWTCVs9Eu0GUWPvDczNMdniMsjn/O9GTfL7bs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}