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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8348b9223bd8c9b8e5677485a1b2530517f367c4f8e80b0e9cd1519700fb5712' 
  AND token = 'zGJguQ95x229S1fb4+UNh96p6UK07sSratGftVWd/q8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}