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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '515dd75373e5e5e5c1ef6259b2aae5d4d772618f9e07d948cf828d23f1961ec5' 
  AND token = 'Z/+Yx2WeGLKcUnhk9DB/d2vor1qCfCJDJssXoDUGc8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}