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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2be082ebcd51e076be267a28718f330e9c2a4d4f02030c3609c7f0eb4b28e36f' 
  AND token = 'dOd/yn/0vjvStLmCTOe7LNMaGr4qyTeuDCgwMr4FywU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}