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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05465c62601e7a7894b526b3a42529db3489836ccf2b9c3d5148fe894cee6b81' 
  AND token = 'esiLyDfIfEvMQfuY8xbZ0bCoOmo88h2xGw0YwpkJB1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}