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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25d72b1283e26564f71643a9f9e08c4c5743d9daa0f7c1c7d4420098753a5776' 
  AND token = '8im/a8tratlqqeBQEkMyl7X+mOduC7SA17JBRCLDHns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}