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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86b2b0c21e13545a99bd7cdd73dc693eb5d216034d19a8311716db6ee99fea64' 
  AND token = 'DciGCa87Fz3ZEf4X7rxiMsqZYeCu2q9Bd8rrT/ieAXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}