SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '346ff89394807adca980effc17f698bd5f988dab438c66e7d2b812733a825e0e' 
  AND token = 'bpqOYRMdm7P8/OFV1Ui2K4+TxUrVkH+8bPHQvCM6N7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}