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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f56181a6dcd79db0339950345a13f4ec4c73f6ce0e3c93a725d395493542225' 
  AND token = '1Edza7p0I9SMPwXZwWGCL3MIOhHNqoqDgFuxud9wtSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}