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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '282f72f4658d6c70675e31b45292404053d904ce6be40b0851a2304eec48e0a6' 
  AND token = 'r3cXKtnjqN0EaVGHwJi4ejD0i4bnvqiiOd75o3laCrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}