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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e760c1dbd968ce75bb98584ecb17353dc5d6c2606d2cb5829c20bfe53f3c170a' 
  AND token = 'ffvM+VrcF7yyRzuVLvYbnS0cOd46+hXihvjAbeOFlAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}