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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '235d193e4eb02ec9d4acc43c2c0407443c1f5c0499ed287197e7715215053d95' 
  AND token = 'ePrf/VP33PrtNUPgN9dtDPLvrN1oh7HfhmwVC5ClmJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}