SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18ad1d87ca2229bcb72f7274342956a6989bcedd15b6ff91b066e8ad23cb4f5c' 
  AND token = 'auZf7XIWB93gNdx92EcnI6Vjd1/xisFMgptwyf43LP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}