SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5565ec3319182768877f7936a107eb09bfb0d120d227d6b9a16e37a175d83492' 
  AND token = 'o7we4DtS0zywYVDHPQJ0KmsEAOh42VjCnu+mygrdmDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}