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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d798f843a37ac68b62ce7a85e4ae9d7bcc7a0a13d5df29c09c5cbbe98f9d322' 
  AND token = '5hg0v7KJkYuXXwYKp3Oya+grg3YDkJr5Bvc+BorlUic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}