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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3a2581558f61601d09e8706c7d5c40fdc3c94aba433fd7da211185913bf4691' 
  AND token = 'Z6ITUS0VT824KByrlJ86+KKttCl5FGr9HX4TSPWrp5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}