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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bd8b9566c58b433ca7d656cf889f41ac69289e678e7ddb6b0695f1bbb99366f' 
  AND token = 'feaUxCzAVS4FCIkmuhzXqPASRoysne1M+GCQmO+zAOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}