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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5621ab30db8e354f7e7b5ecbf078aaa7c554b3ee3b58aa3444dd374278a3bc56' 
  AND token = 'sGjnlZlQU8saFLQqxVmResPOVqlAVD6CGMfaHWY6UBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}