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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea107758d7bb7bf301fc14f6a92caba67d3cc93df3193e8c49cd938e3720b226' 
  AND token = 'dVJ/9e225WKf8JDinEVUa+Mz1UvqHTQIiGOqxzs0CDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}