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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7865f09621962a964a6a677810ed96de30b4b5431e28bd62b990e59121bbf6f5' 
  AND token = 'lrerzIchqHEk02PEEXnQ7O9CIN+F/eU/SSkWwX8R6TA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}