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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4c41e85e2423008c10143af68954715a7a34ef717617dc185dbf30c10a53cb3' 
  AND token = 'zbw8eDkqhYEFTQXlWR9Rk6AzQ+VTMrkE6vsIesXkKg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}