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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44ff187714f7c891e7b2a4d30ae9b72c7e67bdeacf5257175bfa7477feb9b086' 
  AND token = 'NbuzFg+bN8wQoYnLIb9su3NLwJDagyYgzfUjymk+Bho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}