SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '785b933a183fd0d386759488277ab7ccc8bc6d70760c3727e83f480d44853433' 
  AND token = 'ZrsPkJyqK/GBahkFeen/FiuGGVzrHFQlo3OomM/ztnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}