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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44b8f89aa0920af101d2a22bea795348c963c028273a25b593dbe8357087552a' 
  AND token = 'hwXwqASrhbEz4tCjdVEoz3iI/6sJoXMloFQIiuWVg80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}