SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b8526fa579573595e9b7a8d35ae1993455baf04b86cef6cabc28d566baf237f' 
  AND token = 'FMyCyY4zvv5o3MoQAXg9+j4e7iNS+b+GWSxQN1ohVW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}