SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de8a14c39aa745068b6e71a9cf4496abbce2d7882bdba00de4b3442e64ac52ff' 
  AND token = 'vck6/REaYUQSNclejYTMbNaEfbOsdAQD7ZdVJMUXFL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}