SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec6064fc241168e39e784e39a397a23e0807d0aa45aa4bda003ff5096d547d60' 
  AND token = 'u4Xyulgk6sQ2AvbCkV1prfC0WRirfmm51mrGkkbhT5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}