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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a108a5e638f4d97d4ac751d58362cbabab702a0b79f559c24d49267a5b54765d' 
  AND token = 'TuxRuImOpyL55QyodeZS0ODHn5seEDdn3vfAf/zkpFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}