SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72f1ca94471d5442743369ccde43aceebbe08d1a681db9dcda32a2a5be2ed5a3' 
  AND token = 'xRjc2vLVDRAN/YUcHv6jU/ZjEYoh/dX7o93cjs0UIr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}