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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae1ac1ea645fd4ce80d0ccf3218ef788a80483e90af4ab7976ea32888c380d2a' 
  AND token = '1aIKwmiCQ1Y059HQ1P3BA0yLMO3dOmBolzZK8FwH+nw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}