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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3b9eb93ce22971e5262eb160ef1e5027054a6b20ab1f0ac5d592df9de482bb3' 
  AND token = 'qDpDNwf25j/kaZAJ+m1AKnZmjnT1qFRf3ijHm/Mn588=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}