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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b2637f2e54f9ff63d459ebcae72d3abb4c79392c1650b87b57466a8beeac982' 
  AND token = 'ZFnhbSfXudEIBBuCSn1IyGpw9hOYvbqCw3rX80xnck0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}