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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '072c6d74feda234fafdadce9acccbdaeaea37a11c38d539c308a1603a47d9ac3' 
  AND token = 'LzT5OIgsyxN/Q7zRExRWd1Gokzu3yNqs2b1HlBIixuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}