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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '843b2aca698223945f6697fb6cb1a8dcaf5d5604cba86acc5c6b64523c03a895' 
  AND token = '3G/31I0DlMg48aR41ziMpj2LdN9prXcqc7v/rTHXtLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}