SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1afe2e0ef6dd34c38cfe29c97de6b4a915a1d99c48eb151646d123f14c72a6bd' 
  AND token = 'DpC5hLjlo7SGxmSAEFmXH7xXiZwtT6stW+BcB3MB4mQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}