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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '335cb29fa48a0de62f6ec5a3a6fcfc631fc38cbf5c89c5fe216a4584fb2c2f55' 
  AND token = 'dBJP2x+8/na/5tfW5yOWxKPaRVFcSFY5y/Dymw4KIv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}