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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0225454519c87435f85c7b0ed2094d5573f1f3ef7fde26554fa64dbb3d274c8f' 
  AND token = 'wrGkDI2IWidUE3tSnU1ykcBX8D2+inKy21YEhGjcHEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}