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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40db9cfbc80719941446278777d35b7b0af1ef7a8aac37358171689bee9ae5d0' 
  AND token = 'YuHIN+Ilf1DxsgAw0dEbkmWnSGbhHt+iMk52d/1/bBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}