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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15f99c8012308730c8c3936bfd5ca39a9be997d1c03d2206f1cb16f9106adbbf' 
  AND token = 'Y/ro+LLe/EdLJfU9R5Zs1gusQFVb52K5ap77zPEGsyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}