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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5daec8f8babce134e697409d3c17d100aa6171649379cc7ba3d5e7f9259c090a' 
  AND token = 'M4+y+XzEkH8pPTvjkaVX/Cod/ox6mQ4N/yDq4Psvin4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}