SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '440a2e5726481340f26fc05d295f1d256d14a5ac4de0f0526f536c0958c78a8b' 
  AND token = 'hE/T49Sk8aqTtgaG4pjp8hSlDZgiHpY52I23rOib0AM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}