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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f1ddf32e1923469fdc0350fb6475b7880c1ba06dac1298e0200500a0b28a480' 
  AND token = 'Zzh4E+vnhyWiskfRxuvSVdwb3qi93gonK+u2+c+LbAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}