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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9459d427c1d202feccd2b6fd8f7415f57981dbd3223f3d04e7ff1b952abeac9' 
  AND token = 'eKHIINPL3Pmqx+aUjv6xfCeJLw8k9rrf3gakkV32kyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}