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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '942f5864aaeb16e3cd8a3107f2fb39917c2ff5790d9675f682a7166fd5c0b625' 
  AND token = 'rYIdcD7f/xTNe+TNoW8OJsyG+TOfEOyF7gmAmcHW0Hs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}