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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c52c3a03015909f4df167869c17fb32b5d32b0d8bdcae9b8396a29ace71ed662' 
  AND token = 'IUSAw7H7WJ/bPYGC0o1UwtBvAUc1iZlEgpsAgFRsWDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}