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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecb85a8e7f76120f5d36e8ff32fbcea57973471163a1d215e1fd1dddcca08b49' 
  AND token = 'mAA+eqFmtlfzzpUGyg3vl4JIhuqI1AuBAHDddyokGEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}